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> 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > PARD6A / PAR6 Antibody (C-Terminus)品牌 |
Leading Biology | 貨號(hào) |
APG01007G |
產(chǎn)品分類(lèi) |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PARD6A / PAR6 Antibody (C-Terminus).
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分子量 |
37kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Cell membrane. Cell projection, ruffle. Cell junction, tight junction. Note=Colocalizes with GTP- bound CDC42 or RAC1 at membrane ruffles and with PARD3 and PRKCI at epithelial tight junctions
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宿主 |
Goat
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
Human PARD6A / PAR6. This antibody is expected to recognise both reported isoforms (NP_058644.1; NP_001032358.1).
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通用名 |
PAR6A
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基因ID |
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UniProt ID |
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功能 |
Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in the formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
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總結(jié) |
Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in the formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
IHC-P, E
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稀釋方法 |
ELISA (1:8000), IHC-P (5 μg/ml),
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圖像 |
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說(shuō)明書(shū) |
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數(shù)量 |
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