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> 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > TNFRSF1B / TNFR2 Antibody (C-Terminus)品牌 |
Leading Biology | 貨號(hào) |
APR02351G |
產(chǎn)品分類(lèi) |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TNFRSF1B / TNFR2 Antibody (C-Terminus).
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分子量 |
48kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Isoform 1: Cell membrane; Single-pass type I membrane protein Tumor necrosis factor-binding protein 2: Secreted
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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通用名 |
TNFBR, TNFR2
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基因ID |
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UniProt ID |
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功能 |
Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
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總結(jié) |
Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P
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稀釋方法 |
IHC-P (10 μg/ml), WB (1-2 μg/ml),
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圖像 |
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說(shuō)明書(shū) |
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數(shù)量 |
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