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NALP1 / NLRP1 Antibody (C-Terminus)

APR02275G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR02275G		50 μg / ￥4950

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NALP1 / NLRP1 Antibody (C-Terminus)

品牌	Leading Biology	貨號	APR02275G
產(chǎn)品分類	Polyclonal Antibodies	研究領域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NALP1 / NLRP1 Antibody (C-Terminus).
分子量	166kDa
細胞定位	Antigen Cellular Localization: Cytoplasm. Nucleus
宿主	Rabbit
種屬反應性	Human
靶點	peptide corresponding to 13 amino acids near the carboxy-terminus of human NALP1
通用名	CARD7, DEFCAP, KIAA0926, NAC, NALP1
基因ID	22861
UniProt ID	Q9C000
功能	Able to form cytoplasmic structures termed death effector filaments. Enhances APAF1 and cytochrome c-dependent activation of pro-caspase-9 and consecutive apoptosis. Stimulates apoptosis through activation of caspase-3. Involved in activation of caspase-1 and caspase-5 as part of the NALP1 inflammasome complex which leads to processing and release of IL1B and IL18. Binds ATP.
總結	Able to form cytoplasmic structures termed death effector filaments. Enhances APAF1 and cytochrome c-dependent activation of pro-caspase-9 and consecutive apoptosis. Stimulates apoptosis through activation of caspase-3. Involved in activation of caspase-1 and caspase-5 as part of the NALP1 inflammasome complex which leads to processing and release of IL1B and IL18. Binds ATP.
形式	Liquid
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應用	WB, IHC-P, IF, ICC
稀釋方法	IHC-P (2.5 μg/ml), WB (1-2 μg/ml),
圖像	Immunocytochemistry of NALP1 in K562 cells with NALP1 antibody at 10 ug/ml. Immunofluorescence of NALP1 in K562 cells with NALP1 antibody at 20 ug/ml. Anti-NLRP1 / NALP1 antibody IHC of human brain, cortex.
說明書	Product Datasheet Protocol
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