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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > MBL2 Antibody (C-term)

MBL2 Antibody (C-term)

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APR06937G 100 μl / ¥4950

MBL2 Antibody (C-term)

品牌

Leading Biology

貨號(hào)

APR06937G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MBL2 Antibody (C-term).

分子量

H=26 KDa

細(xì)胞定位

Antigen Cellular Localization: Secreted.

宿主

Rabbit

種屬反應(yīng)性

Human

免疫原

188-222 aa

靶點(diǎn)

This MBL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-222 amino acids from the C-terminal region of human MBL2.

通用名

COLEC1, MBL

基因ID

UniProt ID

功能

Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.

總結(jié)

This gene encodes the soluble mannose-binding lectin ormannose-binding protein found in serum. The protein encoded belongsto the collectin family and is an important element in the innateimmune system. The protein recognizes mannose andN-acetylglucosamine on many microorganisms, and is capable ofactivating the classical complement pathway. Deficiencies of thisgene have been associated with susceptibility to autoimmune andinfectious diseases.

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IF, IHC-P

稀釋方法

IHC-P~~1:10~50 WB~~1:1000 IF~~1:10~50

圖像

MBL2 Antibody (C-term) (Cat. APR06937G)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MBL2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

All lanes : Anti-MBL2 Antibody (C-term) at 1:1000 dilution Lane 1: HepG2 whole cell lysate Lane 2: A549 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 26 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Confocal immunofluorescent analysis of MBL2 Antibody (C-term)( APR06937G) with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

說明書

數(shù)量

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