品牌 |
Leading Biology |
貨號 |
APR06936G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CRABP2 Antibody (C-term).
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分子量 |
H=16;M=16;R=16 KDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Endoplasmic reticulum. Nucleus. Note=Upon ligand binding, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
102-136 aa
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靶點(diǎn) |
This CRABP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-136 amino acids from the C-terminal region of human CRABP2.
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基因ID |
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UniProt ID |
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功能 |
Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors.
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總結(jié) |
A number of specific carrier proteins for members of the vitamin A family have been discovered. Cellular retinoic acid binding proteins (CRABP) are low molecular weight proteins whose precise function remains unknown. The inducibility of the CRABP2 gene suggests that this isoform is important in retinoic acid-mediated regulation of human skin growth and differentiation. It has been postulated that the CRABP2 gene is transcriptionally regulated by a newly synthesized regulatory protein. [provided by RefSeq].
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB
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稀釋方法 |
WB~~1:1000
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圖像 |
All lanes : Anti-CRABP2 Antibody (C-term) at 1:1000 dilution
Lane 1: MCF-7 whole cell lysate
Lane 2: MDA-MB-453 whole cell lysate
Lysates/proteins at 20 μg per lane.
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.
Predicted band size : 16 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
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說明書 |
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數(shù)量 |
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