HAVCR2 Antibody (Center)

APR04502G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢(xún)價(jià)
APR04502G		100 μl / ￥4950

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HAVCR2 Antibody (Center)

品牌	Leading Biology	貨號(hào)	APR04502G
產(chǎn)品分類(lèi)	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HAVCR2 Antibody (Center).
分子量	33394 Da
細(xì)胞定位	Antigen Cellular Localization: Membrane; Single-pass type I membrane protein
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	167-194 aa
靶點(diǎn)	This HAVCR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 167-194 amino acids from the Central region of human HAVCR2.
亞型	Rabbit Ig
通用名	TIM3, TIMD3
基因ID	84868
UniProt ID	Q8TDQ0
功能	Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Receptor for LGALS9.
總結(jié)	CD4 (MIM 186940)-positive T helper lymphocytes can bedivided into types 1 (Th1) and 2 (Th2) on the basis of theircytokine secretion patterns. Th1 cells and their associatedcytokines are involved in cell-mediated immunity to intracellularpathogens and delayed-type hypersensitivity reactions, whereas Th2cells are involved in the control of extracellular helminthicinfections and the promotion of atopic and allergic diseases. The 2types of cells also cross-regulate the functions of the other. TIM3is a Th1-specific cell surface protein that regulates macrophageactivation and enhances the severity of experimental autoimmuneencephalomyelitis in mice.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
圖像	All lanes : Anti-HAVCR2 Antibody (Center) at 1:2000 dilution Lane 1: T47D whole cell lysates Lane 2: human kidney lysates Lane 3: KG-1 whole cell lysates Lane 4: human liver lysates Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 33 kDa Blocking/Dilution buffer: 5% NFDM/TBST. All lanes : Anti-HAVCR2 Antibody (Center) at 1:2000 dilution Lane 1: T47D whole cell lysates Lane 2: KG-1 whole cell lysates Lane 3: human liver lysates Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 33 kDa Blocking/Dilution buffer: 5% NFDM/TBST. HAVCR2 Antibody (Center) (Cat. APR04502G) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the HAVCR2 antibody detected the HAVCR2 protein (arrow).
說(shuō)明書(shū)	Product Datasheet Protocol
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