全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR03811G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality IL1RL2 Antibody (Center).
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分子量 |
65405 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
257-286 aa
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靶點 |
This IL1RL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 257-286 amino acids from the Central region of human IL1RL2.
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亞型 |
Rabbit Ig
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通用名 |
IL1RRP2
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基因ID |
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UniProt ID |
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功能 |
Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways (By similarity). The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL- 23/IL-17/IL-22 pathway.
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總結(jié) |
The protein encoded by this gene is a member of theinterleukin 1 receptor family. An experiment with transient geneexpression demonstrated that this receptor was incapable of bindingto interleukin 1 alpha and interleukin 1 beta with high affinity.This gene and four other interleukin 1 receptor family genes,including interleukin 1 receptor, type I (IL1R1), interleukin 1receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1),and interleukin 18 receptor 1 (IL18R1), form a cytokine receptorgene cluster in a region mapped to chromosome 2q12. [provided byRefSeq].
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, FC, E
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稀釋方法 |
WB~~1:1000
FC~~1:10~50
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圖像 |
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說明書 |
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數(shù)量 |
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