全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR03713G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PREX1 Antibody (C-term).
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分子量 |
186203 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm, cytosol. Cell membrane. Note=Mainly cytosolic. Some amount is apparently associated to the plasma membrane
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
1134-1163 aa
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靶點(diǎn) |
This PREX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1134-1163 amino acids from the C-terminal region of human PREX1.
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亞型 |
Rabbit Ig
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通用名 |
KIAA1415
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基因ID |
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UniProt ID |
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功能 |
Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils.
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總結(jié) |
The protein encoded by this gene acts as a guaninenucleotide exchange factor for the RHO family of small GTP-bindingproteins (RACs). It has been shown to bind to and activate RAC1 byexchanging bound GDP for free GTP. The encoded protein, which isfound mainly in the cytoplasm, is activated byphosphatidylinositol-3,4,5-trisphosphate and the beta-gammasubunits of heterotrimeric G proteins.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
IHC-P, WB, FC, E
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稀釋方法 |
IHC-P~~1:10~50
WB~~1:1000
FC~~1:10~50
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圖像 |
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說明書 |
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數(shù)量 |
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