品牌 |
Leading Biology |
貨號(hào) |
APR06078G |
產(chǎn)品分類(lèi) |
Polyclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Enterokinase/Enteropeptidase Antibody (C-term).
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分子量 |
112935 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass type II membrane protein
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
972-1002 aa
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靶點(diǎn) |
This Enterokinase/Enteropeptidase antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 972~1002 amino acids from the C-terminal region of human enteropeptidase.
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亞型 |
Rabbit Ig
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通用名 |
ENTK, PRSS7
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基因ID |
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UniProt ID |
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功能 |
Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.
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總結(jié) |
This enzyme converts the pancreatic proenzyme trypsinogen to trypsin, which activates other proenzymes including chymotrypsinogen and procarboxypeptidases. The precursor protein is cleaved into two chains that form a heterodimer linked by a disulfide bond. This protein is a member of the trypsin family of peptidases. Mutations in this gene cause enterokinase deficiency, a malabsorption disorder characterized by diarrhea and failure to thrive.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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圖像 |
Anti-Enteropeptidase Antibody (C-term) at 1:1000 dilution + Jurkat whole cell lysate
Lysates/proteins at 20 μg per lane.
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.
Predicted band size : 113 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
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說(shuō)明書(shū) |
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數(shù)量 |
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