品牌 |
Leading Biology | 貨號(hào) |
APR05894G |
產(chǎn)品分類(lèi) |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality S100A6 Antibody (C-term).
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分子量 |
10180 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus envelope. Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse
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免疫原 |
37-67 aa
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靶點(diǎn) |
This S100A6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-67 amino acids from the C-terminal region of human S100A6.
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亞型 |
Rabbit Ig
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通用名 |
CACY
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基因ID |
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UniProt ID |
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功能 |
May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative.
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總結(jié) |
S100A6 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, FC, E
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稀釋方法 |
WB~~1:1000
FC~~1:10~50
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圖像 |
Western blot analysis of S100A6 antibody (C-term) (Cat.APR05894G) in mouse lung tissue lysates (35ug/lane). S100A6 (arrow) was detected using the purified Pab. Western blot analysis of S100A6 (arrow) using rabbit polyclonal S100A6 Antibody (C-term) (Cat. APR05894G).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the S100A6 gene (Lane 2) (Origene Technologies). S100A6 Antibody (C-term) (Cat. APR05894G) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
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說(shuō)明書(shū) |
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數(shù)量 |
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