品牌 |
Leading Biology |
貨號 |
APR05870G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality BAR2 Antibody (S261).
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分子量 |
46459 Da
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細胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein Note=Colocalizes with VHL at the cell membrane
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse
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免疫原 |
236-264 aa
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靶點 |
This BAR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-264 amino acids from human BAR2.
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亞型 |
Rabbit Ig
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通用名 |
ADRB2R, B2AR
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基因ID |
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UniProt ID |
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功能 |
Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
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總結(jié) |
Beta-2-adrenergic receptor is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:10~50
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圖像 |
Western blot analysis of anti-BAR2 Antibody (S261) (Cat.APR05870G) in mouse kidney lysates (35ug/lane). BAR2 (arrow) was detected using the purified Pab.
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with BAR2 Antibody (S261) (Cat.APR05870G), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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說明書 |
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數(shù)量 |
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