beta 2 Adrenergic Receptor (BAR2) Antibody (N-term)

APR05869G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR05869G		100 μl / ￥4950

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beta 2 Adrenergic Receptor (BAR2) Antibody (N-term)

品牌	Leading Biology	貨號(hào)	APR05869G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality beta 2 Adrenergic Receptor (BAR2) Antibody (N-term).
分子量	46459 Da
細(xì)胞定位	Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein Note=Colocalizes with VHL at the cell membrane
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	1-30 aa
靶點(diǎn)	This beta 2 Adrenergic Receptor (BAR2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human beta 2 Adrenergic Receptor (BAR2).
亞型	Rabbit Ig
通用名	ADRB2R, B2AR
基因ID	154
UniProt ID	P07550
功能	Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
總結(jié)	This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
圖像	Western blot analysis of anti-BAR2 Antibody (N-term)(Cat. APR05869G) in HL60 cell line lysates (35ug/lane). BAR2(arrow) was detected using the purified Pab.
說(shuō)明書(shū)	Product Datasheet Protocol
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beta 2 Adrenergic Receptor (BAR2) Antibody (N-term)