ERN2 Antibody (C-term)

APR05847G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR05847G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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ERN2 Antibody (C-term)

品牌	Leading Biology	貨號(hào)	APR05847G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ERN2 Antibody (C-term).
分子量	102480 Da
細(xì)胞定位	Antigen Cellular Localization: Endoplasmic reticulum membrane; Single-pass type I membrane protein
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	781-810 aa
靶點(diǎn)	This ERN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 781-810 amino acids from the C-terminal region of human ERN2.
亞型	Rabbit Ig
基因ID	10595
UniProt ID	Q76MJ5
功能	Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins.
總結(jié)	ERN2 induces translational repression through 28S ribosomal RNA cleavage in response to endoplasmic reticulum (ER) stress. This pro-apoptotic appears to play no role in the unfolded-protein response, unlike closely related proteins. Overexpression of ERN2 activates both BiP and CHOP expression, and also leads to the development of programmed cell death. It has been suggested that Ern2 plays a role in multiple facets of the ER stress response in mammalian cells.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
圖像	The anti-ERN2 Pab (Cat. APR05847G) is used in Western blot to detect ERN2 in mouse liver tissue lysate
說(shuō)明書(shū)	Product Datasheet Protocol
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