Phospho-AMOT(S1041) Antibody

APR05240G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR05240G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

Tel: 400-965-8633
Tel: 010-56256916
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Phospho-AMOT(S1041) Antibody

品牌	Leading Biology	貨號(hào)	APR05240G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-AMOT(S1041) Antibody.
分子量	118085 Da
細(xì)胞定位	Antigen Cellular Localization: Cell junction, tight junction. Note=Localized on the cell surface May act as a transmembrane protein
宿主	Rabbit
種屬反應(yīng)性	Human
靶點(diǎn)	This AMOT Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1041 of human AMOT.
亞型	Rabbit Ig
通用名	KIAA1071
基因ID	154796
UniProt ID	Q4VCS5
功能	Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions.
總結(jié)	This gene belongs to the motin family of angiostatinbinding proteins characterized by conserved coiled-coil domains andC-terminal PDZ binding motifs. The encoded protein is expressedpredominantly in endothelial cells of capillaries as well as largervessels of the placenta where it may mediate the inhibitory effectof angiostatin on tube formation and the migration of endothelialcells toward growth factors during the formation of new bloodvessels. Alternative splicing results in multiple transcriptvariants encoding different isoforms.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	DB, E
稀釋方法	DB~~1:500
圖像	Dot blot analysis of Phospho-AMOT-S1041 Antibody Phospho-specific Pab (Cat. APR05240G) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.
說明書	Product Datasheet Protocol
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