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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > FIGLA Antibody (Center)

FIGLA Antibody (Center)

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APR04274G 100 μl / ¥4950

FIGLA Antibody (Center)

品牌

Leading Biology

貨號(hào)

APR04274G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FIGLA Antibody (Center).

分子量

24123 Da

細(xì)胞定位

Antigen Cellular Localization: Nucleus.

宿主

Rabbit

種屬反應(yīng)性

Human

免疫原

108-137 aa

靶點(diǎn)

This FIGLA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 108-137 amino acids from the Central region of human FIGLA.

亞型

Rabbit Ig

通用名

BHLHC8

基因ID

UniProt ID

功能

Germline specific transcription factor implicated in postnatal oocyte-specific gene expression. Plays a key regulatory role in the expression of multiple oocyte-specific genes, including those that initiate folliculogenesis and those that encode the zona pellucida (ZP1, ZP2 and ZP3) required for fertilization and early embryonic survival. Essential for oocytes to survive and form primordial follicles. The persistence of FIGLA in adult females suggests that it may regulate additional pathways that are essential for normal ovarian development. Binds to the E- box (5'-CANNTG-3') of the ZPs (ZP1, ZP2, ZP3) promoters.

總結(jié)

This gene encodes a protein that functions in postnataloocyte-specific gene expression. The protein is a basichelix-loop-helix transcription factor that regulates multipleoocyte-specific genes, including genes involved in folliculogenesisand those that encode the zona pellucida. Mutations in this genecause premature ovarian failure type 6.

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, E

稀釋方法

WB~~1:1000

圖像

All lanes : Anti-FIGLA Antibody (Center) at 1:1000 dilution Lane 1: human ovary lysate Lane 2: T47D whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 24 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

說明書

數(shù)量

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