全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR04235G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CRISP1 Antibody (C-term).
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分子量 |
28481 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Note=Located in the lumen and epithelium of distal ductus efferentes and epididymal ducts, and on the postacrosomal region of the sperm head
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
162-191 aa
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靶點 |
This CRISP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-191 amino acids from the C-terminal region of human CRISP1.
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亞型 |
Rabbit Ig
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通用名 |
AEGL1
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基因ID |
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UniProt ID |
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功能 |
May have a role in sperm-egg fusion and maturation.
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總結(jié) |
Fertilization consists of a sequence of specific cell-cellinteractions culminating in the fusion of the sperm and egg plasmamembranes. Recognition, binding, and fusion occur through theinteraction of complementary molecules that are localized tospecific domains of the sperm and egg plasma membranes. In thesperm, the postacrosomal region or equatorial segment is involvedin sperm-egg plasma membrane fusion. The protein encoded by thisgene is a member of the cysteine-rich secretory protein (CRISP)family. This protein is expressed in the epididymis, is secretedinto the epididymal lumen, and binds to the postacrosomal region ofthe sperm head where it plays a role at fertilization in sperm-eggfusion through complementary sites localized on the egg surface.Two isoforms are encoded by transcript variants of this gene.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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圖像 |
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說明書 |
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數(shù)量 |
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