品牌 |
Leading Biology | 貨號(hào) |
APR04234G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MYH7 Antibody (N-term).
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分子量 |
223097 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm, myofibril. Note=Thick filaments of the myofibrils
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse
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免疫原 |
185-211 aa
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靶點(diǎn) |
This MYH7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-211 amino acids from the N-terminal region of human MYH7.
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亞型 |
Rabbit Ig
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通用名 |
MYHCB
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基因ID |
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UniProt ID |
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功能 |
Muscle contraction.
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總結(jié) |
Muscle myosin is a hexameric protein containing 2 heavychain subunits, 2 alkali light chain subunits, and 2 regulatorylight chain subunits. This gene encodes the beta (or slow) heavychain subunit of cardiac myosin. It is expressed predominantly innormal human ventricle. It is also expressed in skeletal muscletissues rich in slow-twitch type I muscle fibers. Changes in therelative abundance of this protein and the alpha (or fast) heavysubunit of cardiac myosin correlate with the contractile velocityof cardiac muscle. Its expression is also altered during thyroidhormone depletion and hemodynamic overloading. Mutations in thisgene are associated with familial hypertrophic cardiomyopathy,myosin storage myopathy, dilated cardiomyopathy, and Laingearly-onset distal myopathy.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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圖像 |
Anti-MYH7 Antibody (N-term) at 1:1000 dilution + human skeletal muscle lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 223 kDa Blocking/Dilution buffer: 5% NFDM/TBST. MYH7 Antibody (N-term) (Cat. APR04234G) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the MYH7 antibody detected the MYH7 protein (arrow). |
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說(shuō)明書(shū) |
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數(shù)量 |
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