全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR04226G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SAMHD1 Antibody (Center).
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分子量 |
72201 Da
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細胞定位 |
Antigen Cellular Localization:
Nucleus
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宿主 |
Rabbit
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種屬反應性 |
Human
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免疫原 |
204-230 aa
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靶點 |
This SAMHD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 204-230 amino acids from the Central region of human SAMHD1.
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亞型 |
Rabbit Ig
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通用名 |
MOP5
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基因ID |
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UniProt ID |
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功能 |
Host restriction nuclease that blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May function by reducing the cellular dNTP levels to levels too low for retroviral reverse transcription to occur. May play a role in mediating proinflammatory responses to TNF-alpha signaling.
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總結 |
This gene may play a role in regulation of the innateimmune response. The encoded protein is upregulated in response toviral infection and may be involved in mediation of tumor necrosisfactor-alpha proinflammatory responses. Mutations in this gene havebeen associated with Aicardi-Goutieres syndrome. [provided byRefSeq].
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, E
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稀釋方法 |
WB~~1:1000
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圖像 |
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說明書 |
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數(shù)量 |
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