品牌 |
Leading Biology | 貨號(hào) |
APR04173G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MMRN1 Antibody (N-term).
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分子量 |
138110 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Secreted.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
179-207 aa
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靶點(diǎn) |
This MMRN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-207 amino acids from the N-terminal region of human MMRN1.
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亞型 |
Rabbit Ig
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通用名 |
ECM, EMILIN4, GPIA*, MMRN
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基因ID |
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UniProt ID |
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功能 |
Carrier protein for platelet (but not plasma) factor V/Va. Plays a role in the storage and stabilization of factor V in platelets. Upon release following platelet activation, may limit platelet and plasma factor Va-dependent thrombin generation. Ligand for integrin alpha-IIb/beta-3 and integrin alpha-V/beta-3 on activated platelets, and may function as an extracellular matrix or adhesive protein.
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總結(jié) |
Multimerin is a massive, soluble protein found inplatelets and in the endothelium of blood vessels. It is comprisedof subunits linked by interchain disulfide bonds to form large,variably sized homomultimers. Multimerin is a factor V/Va-bindingprotein and may function as a carrier protein for platelet factorV. It may also have functions as an extracellular matrix oradhesive protein. Recently, patients with an unusualautosomal-dominant bleeding disorder (factor V Quebec) were foundto have a deficiency of platelet multimerin.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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圖像 |
Western blot analysis of lysates from HLVEC, HUVEC cell line (from left to right), using MMRN1 Antibody (N-term)(APR04173G). APR04173G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane. |
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說明書 |
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數(shù)量 |
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