全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR03909G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality NCK2 Antibody (N-term).
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分子量 |
42915 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Endoplasmic reticulum
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
63-92 aa
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靶點(diǎn) |
This NCK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-92 amino acids from the N-terminal region of human NCK2.
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亞型 |
Rabbit Ig
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通用名 |
GRB4
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基因ID |
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UniProt ID |
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功能 |
Adapter protein which associates with tyrosine- phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in ELK1- dependent transcriptional activation in response to activated Ras signaling.
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總結(jié) |
This gene encodes a member of the NCK family of adaptorproteins. The protein contains three SH3 domains and one SH2domain. The protein has no known catalytic function but has beenshown to bind and recruit various proteins involved in theregulation of receptor protein tyrosine kinases. It is throughthese regulatory activities that this protein is believed to beinvolved in cytoskeletal reorganization. Alternate transcriptionalsplice variants, encoding different isoforms, have beencharacterized.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:10~50
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圖像 |
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說明書 |
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數(shù)量 |
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