全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR03868G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SLC11A2 Antibody (Center).
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分子量 |
62266 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Endosome membrane; Multi-pass membrane protein. Mitochondrion outer membrane; Multi-pass membrane protein
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Mouse, Rat
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免疫原 |
262-291 aa
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靶點(diǎn) |
This SLC11A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-291 amino acids from the Central region of human SLC11A2.
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亞型 |
Rabbit Ig
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通用名 |
DCT1, DMT1, NRAMP2
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基因ID |
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UniProt ID |
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功能 |
Important in metal transport, in particular iron. Can also transport manganese, cobalt, cadmium, nickel, vanadium and lead. Involved in apical iron uptake into duodenal enterocytes. Involved in iron transport from acidified endosomes into the cytoplasm of erythroid precursor cells. May play an important role in hepatic iron accumulation and tissue iron distribution. May serve to import iron into the mitochondria.
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總結(jié) |
This gene encodes a member of the solute carrier family 11protein family. The product of this gene transports divalent metalsand is involved in iron absorption. Mutations in this gene areassociated with hypochromic microcytic anemia with iron overload. Arelated solute carrier family 11 protein gene is located onchromosome 2. Multiple transcript variants encoding differentisoforms have been found for this gene.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IF, E
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稀釋方法 |
WB~~1:2000
IF~~1:10~50
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圖像 |
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說明書 |
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數(shù)量 |
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