HPSE2 Antibody (C-term)

APR03760G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR03760G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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HPSE2 Antibody (C-term)

品牌	Leading Biology	貨號	APR03760G
產(chǎn)品分類	Polyclonal Antibodies	研究領域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HPSE2 Antibody (C-term).
分子量	66596 Da
細胞定位	Antigen Cellular Localization: Secreted, extracellular space, extracellular matrix
宿主	Rabbit
種屬反應性	Human
免疫原	451-480 aa
靶點	This HPSE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 451-480 amino acids from the C-terminal region of human HPSE2.
亞型	Rabbit Ig
通用名	HPA2
基因ID	60495
UniProt ID	Q8WWQ2
功能	Binds heparin and heparan sulfate with high affinity, but lacks heparanase activity. Inhibits HPSE, possibly by competing for its substrates (in vitro).
總結(jié)	Endoglycosidase which is a cell surface and extracellular matrix-degrading enzyme. Cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Also implicated in the extravasation of leukocytes and tumor cell lines. Due to its contribution to metastasis and angiogenesis, it is considered to be a potential target for anti-cancer therapies.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應用	WB, IHC-P, E
稀釋方法	WB~~1:1000 IHC-P~~1:10~50
圖像	Western blot analysis of lysates from HeLa, Jurkat cell line (from left to right), using HPSE2 Antibody (C-term)(Cat. APR03760G). APR03760G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane. HPSE2 Antibody (C-term) (Cat. APR03760G)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HPSE2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
說明書	Product Datasheet Protocol
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