品牌 |
Leading Biology | 貨號(hào) |
APR03647G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SAMD8 Antibody (N-term).
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分子量 |
48321 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse
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免疫原 |
38-67 aa
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靶點(diǎn) |
This SAMD8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-67 amino acids from the N-terminal region of human SAMD8.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Sphingomyelin synthases synthesize sphingolipids through transfer of a phosphatidyl head group on to the primary hydroxyl of ceramide. SAMD8 is an endoplasmic reticulum (ER) transferase that has no sphingomyelin synthase activity but can convert phosphatidylethanolamine (PE) and ceramide to ceramide phosphoethanolamine (CPE) albeit with low product yield. Appears to operate as a ceramide sensor to control ceramide homeostasis in the endoplasmic reticulum rather than a converter of ceramides. Seems to be critical for the integrity of the early secretory pathway.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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圖像 |
Anti-SAMD8 Antibody (N-term) at 1:1000 dilution + human heart lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 48 kDa Blocking/Dilution buffer: 5% NFDM/TBST. Western blot analysis of SAMD8 Antibody (N-term) Pab (Cat. APR03647G) pre-incubated without(lane 1) and with(lane 2) blocking peptide in mouse liver tissue lysate. SAMD8 Antibody (N-term) (arrow) was detected using the purified Pab. |
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說(shuō)明書 |
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數(shù)量 |
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