品牌 |
Leading Biology |
貨號 |
APR03503G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
|
產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality BCL11B Antibody (Center).
|
分子量 |
95519 Da
|
細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus.
|
宿主 |
Rabbit
|
種屬反應(yīng)性 |
Human
|
免疫原 |
307-334 aa
|
靶點(diǎn) |
This BCL11B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 307-334 amino acids from the Central region of human BCL11B.
|
亞型 |
Rabbit Ig
|
通用名 |
CTIP2, RIT1
|
基因ID |
|
UniProt ID |
|
功能 |
Tumor-suppressor protein involved in T-cell lymphomas. May function on the P53-signaling pathway. May be a key regulator of both differentiation and survival during thymocyte development. Repress transcription through direct, TFCOUP2-independent binding to a GC-rich response element (By similarity).
|
總結(jié) |
This gene encodes a C2H2-type zinc finger protein and isclosely related to BCL11A, a gene whose translocation may beassociated with B-cell malignancies. The specific function of thisgene has not yet been determined. Two alternatively splicedtranscript variants, which encode distinct isoforms, have beenreported.
|
儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
應(yīng)用 |
WB, E
|
稀釋方法 |
WB~~1:16000
|
圖像 |
All lanes : Anti-BCL11B Antibody (Center) at 1:16000 dilution
Lane 1: Jurkat whole cell lysate
Lane 2: MOLT-4 whole cell lysate
Lysates/proteins at 20 μg per lane.
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.
Predicted band size : 96 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
|
說明書 |
|
數(shù)量 |
|