MPP1 Antibody (Center)

APR03467G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR03467G		100 μl / ￥4950

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MPP1 Antibody (Center)

品牌	Leading Biology	貨號(hào)	APR03467G
產(chǎn)品分類(lèi)	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MPP1 Antibody (Center).
分子量	52296 Da
細(xì)胞定位	Antigen Cellular Localization: Membrane; Lipid-anchor. Cell projection, stereocilium. Note=Colocalizes with WHRN at stereocilium tip during hair cell development (By similarity) Colocalizes with MPP5 in the retina, at the outer limiting membrane (OLM). Colocalizes with WHRN in the retina, at the outer limiting membrane (OLM), outer plexifirm layer (OPL), basal bodies and at the connecting cilium (CC). Colocalizes with NF2 in non- myelin-forming Schwann cells.
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	301-327 aa
靶點(diǎn)	This MPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 301-327 amino acids from the Central region of human MPP1.
亞型	Rabbit Ig
通用名	DXS552E, EMP55
基因ID	4354
UniProt ID	Q00013
功能	Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity (By similarity).
總結(jié)	This gene encodes the prototype of the membrane-associatedguanylate kinase (MAGUK) family proteins. MAGUKs interact with thecytoskeleton and regulate cell proliferation, signaling pathways,and intercellular junctions. The encoded protein is an extensivelypalmitoylated membrane phosphoprotein containing a PDZ domain, aSrc homology 3 (SH3) motif, and a guanylate kinase domain. Thisgene product interacts with various cytoskeletal proteins and celljunctional proteins in different tissue and cell types, and may beinvolved in the regulation of cell shape, hair cell development,neural patterning of the retina, and apico-basal polarity and tumorsuppression pathways in non-erythroid cells. Multiple transcriptvariants encoding different isoforms have been found for this gene.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, FC, E
稀釋方法	WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50
圖像	MPP1 Antibody (Center) (Cat. APR03467G) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the MPP1 antibody detected the MPP1 protein (arrow). Western blot analysis of MPP1 (arrow) using rabbit polyclonal MPP1 Antibody (Center) (Cat. APR03467G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the MPP1 gene. MPP1 Antibody (C-term) (Cat. APR03467G) immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MPP1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
說(shuō)明書(shū)	Product Datasheet Protocol
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