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P2Y14 Receptor (extracellular) Antibody品牌 |
Leading Biology | 貨號(hào) |
APR17720G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality P2Y14 Receptor (extracellular) antibody.
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分子量 |
38971 Da
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Rat
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靶點(diǎn) |
Peptide CIELKSELGRKWHKASN, corresponding to amino acid?residues 172-188 of human P2Y14 (Accession# Q15391). 2nd extracellular loop.
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基因ID |
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UniProt ID |
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總結(jié) |
P2Y14 belongs to the P2Y receptor family that is part of the G-protein coupled receptor superfamily. To date eight functional mammalian P2Y receptors have been identified: P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, P2Y13 and P2Y14.The P2Y receptor family mediates the effects of extracellular nucleotides such as ATP, ADP, UTP and in the case of P2Y14 UDP-glucose. UDP-glucose as the other nucleotides can be released to the extracellular milieu as the result of cell damage or by regulated non-lytic mechanisms.P2Y14 is expressed in several tissues including brain, lung and several cells of hematopoietic origin such as T lymphocytes and dendritic cells.The exact function of this receptor in the different tissues has not been clearly established but an involvement in chemotaxis, maturation of immature dendritic cells and neuroimmune regulation has been suggested.Abgent is pleased to offer a highly specific antibody directed against a conserved epitope in the second extracellular loop of the human P2Y14 receptor. Anti-P2Y14 (extracellular) antibody (#AG1064) can be used in Western blot analysis, and will recognize human and mouse samples.
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形式 |
Affinity purified antibody, Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, FC
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稀釋方法 |
WB~~1:200-1:2000
FC~~1:40
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別名 |
P2Y purinoceptor 14, P2Y14, G-protein coupled receptor 105, UDP-glucose receptor, P2RY14, GPR105, KIAA0001
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圖像 |
Western blot analysis of lysate from rat heart tissue lysate, using P2RY14 Antibody( APR17720G). APR17720G was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug. Flow cytometric analysis of Jurkat cells using Park7 (DJ-1) Antibody(green, APR17720G) compared to an isotype control of rabbit IgG(blue). APR17720G was diluted at 1:40 dilution. An Alexa Fluor? 488 goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody. Western blot analysis of rat heart membranes (lanes 1,4), rat brain (lanes 2,5) and rat lung lysates (lanes 3,6): 1-3. Anti-P2Y14 Receptor (extracellular) antibody, ( APR17720G), (1:200). 4-6. Anti-P2Y14 Receptor (extracellular) antibody, preincubated with the control peptide antigen. |
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說明書 |
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數(shù)量 |
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