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> 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > Somatostatin Receptor Type I (extracellular) Antibody品牌 |
Leading Biology | 貨號(hào) |
APR13446G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Somatostatin Receptor Type I (extracellular) antibody.
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分子量 |
42746 Da
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Rat
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靶點(diǎn) |
Peptide CSRGPGSGAADGMEE, corresponding to amino acid?residues 26-40 of rat somatostatin receptor type 1 (Accession# P28646). Extracellular, N-terminus.
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基因ID |
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UniProt ID |
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總結(jié) |
Somatostatin is a small cyclic peptide that is widely expressed throughout the central nervous system and peripheral tissues.1 In peripheral tissues, somatostatin exerts inhibitory effects on secretion processes, whereas in the brain it acts as a neurotransmitter in both stimulatory and inhibitory manner.1, 2Somatostatin mediates its action via six high affinity G-protein coupled receptors (SSTR1, SSTR2a, SSTR2b, SSTR3, SSTR4 and SSTR5) which are encoded by five genes.1,2 Expression of the different receptors is developmentally regulated in a time and tissue-specific manner.2 Somatostatin receptors have been found on a variety of neuroendocrine tumors, such as paragangliomas, carcinoids and breast tumors.3 Synthetic peptide derivatives of somatostatin have been successfully used in the treatment of neuroendocrine malignancies and in in vivo imaging of tumors that are positive to somatostatin receptors.4Abgent is pleased to offer a highly specific antibody directed against the N-terminus domain of the rat SSTR1. Anti-Somatostatin Receptor Type 1 antibody (#AG1021), can be used in western blot analysis, and recognizes SSTR1 in rat samples.
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形式 |
Affinity purified antibody, Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB
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稀釋方法 |
WB~~1:200-1:2000
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別名 |
Somatostatin receptor type 1, SS-1-R, SS1-R, SS1R, SRIF-2, Sstr1
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圖像 |
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說(shuō)明書 |
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數(shù)量 |
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