全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
APG02947G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
|
產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PACS2 antibody.
|
||
分子量 |
Predicted: 98 kDa Observed: 95 kDa
|
||
細(xì)胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum lumen. Mitochondrion
|
||
宿主 |
Rabbit
|
||
種屬反應(yīng)性 |
Human, Mouse, Rat
|
||
靶點(diǎn) |
PACS2; PACS2 antibody is human, mouse and rat reactive. At least three isoforms of PACS2 are known to exist; this antibody will detect all three. PACS2 antibody is predicted to not cross-react with PACS1.
|
||
亞型 |
IgG
|
||
通用名 |
KIAA0602, PACS1L
|
||
基因ID |
|||
UniProt ID |
|||
功能 |
Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.
|
||
總結(jié) |
PACS2 (phosphofurin acidic cluster sorting protein-2), PACS1L, is an 889 amino acid protein that localizes to both the mitochondrion and the lumen of the endoplasmic reticulum (ER) and belongs to the PACS family (1,2). It is expressed in a broad range of tissues with highest expression in skeletal muscle, brain, heart, testis and pancreas (2,). PACS2 interacts with Polycystin-2 and BID and functions as a sorting protein that regulates mitochondria-ER communication and is thought to be involved in ion channel trafficking, specifically direct cluster-containing ion channels to distinct subcellular compartments (3-5).
|
||
形式 |
Liquid
|
||
儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
||
應(yīng)用 |
WB, E
|
||
圖像 |
|
||
說明書 |
|||
數(shù)量 |
|
||
| 選擇 | 品牌 | 貨號(hào) | 產(chǎn)品名稱 | 規(guī)格 | 分類 | 研究領(lǐng)域 | 說明書 | 數(shù)量 | 目錄價(jià) | |
| 1 | Leading Biology | APR05963G | EGFR Antibody (Y1092) | 100 μl | Polyclonal Antibodies |
|
￥4950.00 | 訂購(gòu) 詢價(jià) | ||
| 2 | Leading Biology | APR03116G | BRCA1 Antibody (aa1847-1863) | 100 μl | Polyclonal Antibodies |
|
￥4950.00 | 訂購(gòu) 詢價(jià) | ||
| 3 | Leading Biology | AMM05633G | Bombesin Receptor 2 (extracellular) Antibody | 50 μl | Polyclonal Antibodies |
|
￥6950.00 | 訂購(gòu) 詢價(jià) | ||
| 4 | Leading Biology | APR10986G | AP3B1 Antibody (aa2-14) | 50 μg | Polyclonal Antibodies |
|
￥4950.00 | 訂購(gòu) 詢價(jià) | ||
| 5 | Leading Biology | APR11512G | Bestrophin-1 (extracellular) Antibody | 50 μl | Polyclonal Antibodies |
|
￥6950.00 | 訂購(gòu) 詢價(jià) | ||
| 6 | Leading Biology | APG01407G | A3 Adenosine Receptor Antibody | 50 μl | Polyclonal Antibodies |
|
￥6950.00 | 訂購(gòu) 詢價(jià) |
.jpg)
微信掃描二維碼，隨時(shí)隨地與小諾親密接觸，精彩活動(dòng)，勁爆優(yōu)惠，觸手可得！
銷售-華東區(qū)