SLC29A2 Antibody

AMM07844G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMM07844G		0.1 mg / ￥6950

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安諾倫（北京）生物科技有限公司

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SLC29A2 Antibody

品牌	Leading Biology	貨號	AMM07844G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SLC29A2 antibody.
分子量	Predicted: 50 kDa; Observed: 50 kDa
細(xì)胞定位	Antigen Cellular Localization: Basolateral cell membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein. Note=Localized at the basolateral cell membrane in polarized MDCK cells
宿主	Rabbit
種屬反應(yīng)性	Human
靶點(diǎn)	SLC29A2; SLC29A2 antibody is human specific. SLC29A2 antibody is predicted to not cross-react with other SLC29 proteins.
亞型	IgG
通用名	DER12, ENT2, HNP36
基因ID	3177
UniProt ID	Q14542
功能	Mediates equilibrative transport of purine, pyrimidine nucleosides and the purine base hypoxanthine. Very less sensitive than SLC29A1 to inhibition by nitrobenzylthioinosine (NBMPR), dipyridamole, dilazep and draflazine.
總結(jié)	SLC29A2 is a member of the equilibrative nucleoside transporter family which plays a key role in nucleoside and nucleobase uptake for salvage pathways of nucleotide synthesis (1,2). SLC29A2 is a transmembrane glycoprotein that mediates the cellular uptake of nucleosides from the surrounding medium (3). As a nucleoside transporter, SLC29A2 plays an important role in the uptake of nucleoside-based anti-cancer drugs; polymorphisms of point mutations in the gene encoding this protein may affect the efficacy of these drugs (4).
形式	Liquid
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC, IF, E
圖像	Western blot analysis of SLC29A2 in human bladder tissue lysate with SLC29A2 antibody at 1 μg/ml. Immunohistochemistry of SLC29A2 in human bladder tissue with SLC29A2 antibody at 2.5 μg/mL. Immunofluorescence of SLC29A2 in human bladder tissue with SLC29A2 antibody at 20 μg/ml.
說明書	Product Datasheet Protocol
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