SLC1A7 Antibody

APR10008G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR10008G		0.1 mg / ￥6950

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安諾倫（北京）生物科技有限公司

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Tel: 010-56256916
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SLC1A7 Antibody

品牌	Leading Biology	貨號(hào)	APR10008G
產(chǎn)品分類(lèi)	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SLC1A7 antibody.
分子量	Predicted: 17, 52, 62, 68 kDa Observed: 52 kDa
細(xì)胞定位	Antigen Cellular Localization: Membrane; Multi-pass membrane protein.
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse
靶點(diǎn)	SLC1A7; SLC1A7 antibody is human and mouse reactive. Multiple isoforms of SLC1A7 are known to exist.
亞型	IgG
通用名	EAAT5
基因ID	6512
UniProt ID	O00341
功能	Transports L-glutamate; the L-glutamate uptake is sodium- and voltage-dependent and chloride-independent. Its associated chloride conductance may participate in visual processing.
總結(jié)	The solute carrier family 1 member 7 (SLC1A7) protein was initially identified as a glutamate transporter coupled to a chloride conductance that is expressed primarily in the retina (1). More recent evidence indicates that is it widely expressed in peripheral tissues, also (2). Experiments have shown that SLC1A7 functions as a low-affinity/low-capacity glutamate transport, with an anion channel optimized for anion conductance in the negative voltage range (3). In the retina, SLC1A7 co-localizes with the serum and glucocorticoid dependent kinase SGK1, and its cell surface expression and activity is regulated SGK1 and its isoform SGK3 (4).
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, IF, E
圖像	Western blot analysis of SLC1A7 in C2C12 cell lysate with SLC1A7 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide. Immunohistochemistry of SLC1A7 in mouse kidney tissue with SLC1A7 antibody at 5 μg/ml. Immunofluorescence of SLC1A7 in mouse kidney tissue with SLC1A7 antibody at 20 μg/ml.
說(shuō)明書(shū)	Product Datasheet Protocol
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