BAMBI Antibody

APR15105G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢(xún)價(jià)
APR15105G		0.1 mg / ￥6950

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安諾倫（北京）生物科技有限公司

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Tel: 010-56256916
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BAMBI Antibody

品牌	Leading Biology	貨號(hào)	APR15105G
產(chǎn)品分類(lèi)	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality BAMBI antibody.
分子量	Predicted: 29 kDa Observed: 26 kDa
細(xì)胞定位	Antigen Cellular Localization: Membrane; Single-pass type I membrane protein
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse, Rat
靶點(diǎn)	BAMBI; BAMBI antibody is human, mouse and rat reactive.
亞型	IgG
通用名	NMA
基因ID	25805
UniProt ID	Q13145
功能	Negatively regulates TGF-beta signaling.
總結(jié)	BAMBI (BMP and activin membrane-bound inhibitor homolog, NMA) is a membrane spanning glycoprotein that acts as a negative regulator of TGF-beta signaling during development (1). BAMBI transcription regulation is under the influence of beta-catenin, BMP, smad3 and smad4 (2,3). BAMBI expression can increase in colorectal and hepatocellular carcinomas relative to non-cancerous tissues (4). BAMBI is expressed at high levels during odontogenesis. BAMBI is coexpressed with Bmp-4 during early Xenopus embryogenesis and can be detected in poorly metastatic human melanoma cell lines (5).
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, IF, E
圖像	Western blot analysis of BAMBI in mouse lung tissue lysate with BAMBI antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide. Immunohistochemistry of BAMBI in human lung tissue with BAMBI antibody at 5 μg/ml. Immunofluorescence of BAMBI in human lung tissue with BAMBI antibody at 20 μg/ml.
說(shuō)明書(shū)	Product Datasheet Protocol
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