品牌 |
Leading Biology | 貨號(hào) |
APR15285G |
產(chǎn)品分類(lèi) |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CCR7 antibody.
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分子量 |
Predicted: 42 kDa Observed: 42 kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
CCR7; CCR7 antibody is human specific. CCR7 antibody is predicted to not cross-react with other CCR proteins.
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亞型 |
IgG
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通用名 |
CMKBR7, EBI1, EVI1
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基因ID |
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UniProt ID |
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功能 |
Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.
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總結(jié) |
The CCR7 protein is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation (1,2). The chemokine (C-C motif) ligand 19 (CCL19) has been reported to be a specific ligand of this receptor (3).
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形式 |
Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IF, E
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圖像 |
Western blot analysis of CCR7 in human spleen tissue lysate with CCR7 antibody at 1 μg/ml. Immunohistochemistry of CCR7 in human spleen tissue with CCR7 antibody at 5 μg/mL. Immunofluorescence of CCR7 in human spleen tissue with CCR7 antibody at 20 μg/mL. |
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說(shuō)明書(shū) |
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數(shù)量 |
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