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當(dāng)前位置:首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > TLX2 Antibody

TLX2 Antibody

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢(xún)價(jià)
APR13739G 0.1 mg / ¥6950

TLX2 Antibody

品牌

Leading Biology

貨號(hào)

APR13739G

產(chǎn)品分類(lèi)

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TLX2 antibody.

分子量

Predicted: 31 kDa Observed: 30 kDa

細(xì)胞定位

Antigen Cellular Localization: Nucleus.

宿主

Rabbit

種屬反應(yīng)性

Human, Mouse, Rat

靶點(diǎn)

TLX2; TLX2 antibody is predicted to not cross-react with other TLX proteins.

亞型

IgG

通用名

HOX11L1, NCX

基因ID

UniProt ID

功能

Transcription activator that binds DNA elements with the consensus sequence 5'-CGGTAATTGG-3'. Binds DNA via its homeobox. Required for normal cell death of enteric neurons in the gastrointestinal tract. Required for normal development of the enteric nervous system, and for proper development of normal motility of the gastrointestinal tract (By similarity).

總結(jié)

TLX2 Antibody: The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX2, also known as homeobox11-like 1 (HOX11L1), is a DNA-binding nuclear transcription factor that appears to be crucial for the development of the peripheral nervous system. TLX2 is a downstream target of regulation by both PHOX2A and PHOX2B proteins during intestinal neuronal differentiation. In humans, loss-of-function of TLX2 may play a role in tumorigenesis of gastrointestinal stromal tumors.

形式

Liquid

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC-P, IF, E

圖像

Western blot analysis of TLX2 in rat brain tissue lysate with TLX2 antibody at (A) 0.5 and (B) 1 μg/mL.

Immunohistochemistry of TLX2 in rat brain tissue with TLX2 antibody at 2.5 μg/ml.

Immunofluorescence of TLX2 in rat brain tissue with TLX2 antibody at 20 μg/ml.

說(shuō)明書(shū)

數(shù)量

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