GRIP1 Antibody

APR12278G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR12278G		0.1 mg / ￥6950

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安諾倫（北京）生物科技有限公司

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GRIP1 Antibody

品牌	Leading Biology	貨號(hào)	APR12278G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GRIP1 antibody.
分子量	Predicted: 118 kDa
細(xì)胞定位	Antigen Cellular Localization: Cytoplasmic vesicle. Endoplasmic reticulum. Cell junction, synapse, postsynaptic cell membrane. Note=Cytoplasmic and membrane-associated with vesicles, peri-Golgi complexes and endoplasmic reticulum. Enriched in postsynaptic plasma membrane and postsynaptic densities (By similarity).
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse, Rat
靶點(diǎn)	GRIP1;
亞型	IgG
基因ID	23426
UniProt ID	Q9Y3R0
功能	May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons.
總結(jié)	GRIP1 Antibody: Glutamate receptors play an important role in neural plasticity, development and degeneration. The glutamate receptor interacting proteins, GRIP1 and GRIP2, members of the PDZ domain-containing protein family, mediate the trafficking and membrane organization of a number of transmembrane proteins. GRIP1 and GRIP2 specifically bind to the AMPA receptor subunits, GluR 2/3 and are involved in the targeting of GluR 2/3 to the synapse. GRIP1 is expressed in early development before the expression of AMPA receptors, while GRIP2 expression parallels that of AMPA receptors during later developmental stages. GRIP1 and GRIP2 may be involved in the induction of cerebellar long-term depression (LTD).
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, IF, E
圖像	Western blot analysis of GRIP1 in HeLa cell lysate with GRIP1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide. Immunohistochemistry of GRIP1 in rat brain tissue with GRIP1 antibody at 2.5 μg/ml. Immunofluorescence of GRIP1 in rat brain tissue with GRIP1 antibody at 20 μg/ml.
說(shuō)明書(shū)	Product Datasheet Protocol
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