全部產品分類
品牌 |
Leading Biology | 貨號 |
APR11658G |
產品分類 |
Polyclonal Antibodies | 研究領域 |
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產品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CRB1 antibody.
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分子量 |
Predicted: 142 kDa
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細胞定位 |
Antigen Cellular Localization:
Isoform 1: Apical cell membrane; Single-pass type I membrane protein. Note=Distributed at the apical membrane of all retinal epithelial cells. Located in the apical membrane of the adherens junction in outer limiting membrane (OLM) of the retina
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宿主 |
Rabbit
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種屬反應性 |
Human
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靶點 |
CRB1; Alternatively spliced transcript variants have been observed. CRB1 antibody i spredicted to not cross-react with CRB2.
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亞型 |
IgG
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基因ID |
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UniProt ID |
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功能 |
Plays a role in photoreceptor morphogenesis in the retina. May maintain cell polarization and adhesion.
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總結 |
CRB1 Antibody: CRB1 (Crumbs homolog 1) plays a role in photoreceptor morphogenesis in the retina. It may maintain cell polarization and adhesion. CRB1 is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. The first identified human homolog, CRB1, is expressed in retina and some parts of the brain, leaving room for another homolog to function in epithelial tissues. Mutations in this gene are associated with a severe form of retinitis pigmentosa, RP12, and with Leber congenital amaurosis.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, E
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圖像 |
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說明書 |
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數量 |
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