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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > TMEM106B Antibody

TMEM106B Antibody

貨號 貨期 規(guī)格 / 價格 詢價
APR13745G 0.1 mg / ¥6950

TMEM106B Antibody

品牌

Leading Biology

貨號

APR13745G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TMEM106B antibody.

分子量

Predicted: 30 kDa Observed: 33 kDa

細胞定位

Antigen Cellular Localization: Late endosome membrane; Single-pass type II membrane protein. Lysosome membrane; Single-pass type II membrane protein

宿主

Rabbit

種屬反應(yīng)性

Human

靶點

TMEM106B; This TMEM106B antibody is predicted to have no cross-reactivity to TMEM106A.

亞型

IgG

基因ID

UniProt ID

功能

Involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking via its interaction with MAP6. May act by inhibiting retrograde transport of lysosomes along dendrites. Required for dendrite branching.

總結(jié)

TMEM106B Antibody: Transmembrane protein 106B (TMEM106B) is a single-pass transmembrane protein that is thought to be a novel risk factor for frontotemporal lobar degeneration (FTLD), a group of clinically, pathologically and genetically heterogeneous disorders associated with atrophy in the frontal lobe and temporal lobe of the brain. The actual role of TMEM106B, and that of the closely related protein TMEM106A are still undetermined.

形式

Liquid

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC-P, IF, E

圖像

Western blot analysis of TMEM106B in human brain tissue lysate with TMEM106B antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.

Immunohistochemistry of TMEM106B in human liver tissue with TMEM106B antibody at 2.5 μg/mL.

Immunofluorescence of TMEM106B in human liver tissue with TMEM106A antibody at 20 μg/mL.

說明書

數(shù)量

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