RKHD3 Antibody

AMM07622G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMM07622G		0.1 mg / ￥6950

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安諾倫（北京）生物科技有限公司

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RKHD3 Antibody

品牌	Leading Biology	貨號(hào)	AMM07622G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RKHD3 antibody.
分子量	58832 Da
細(xì)胞定位	Antigen Cellular Localization: Nucleus. Cytoplasm. Cytoplasm, P-body. Cytoplasmic granule. Note=Predominantly expressed in the cytoplasm and shuttles between the cytoplasm and the nucleus through the CRM1 export pathway. Localization to P-bodies is dependent on 14-3-3
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse, Rat
靶點(diǎn)	MEX3B; This antibody is specific for RKHD3 and will not recognize the other RKHD3 family of proteins.
亞型	IgG
通用名	KIAA2009, RKHD3, RNF195
基因ID	84206
UniProt ID	Q6ZN04
功能	RNA-binding protein. May be involved in post- transcriptional regulatory mechanisms.
總結(jié)	RKHD3 Antibody: Rkhd3, also known as MEX3B is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module. MEX3 proteins, including Rkhd3, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway. These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms. Rkhd3 is thought to act as a mechanism to fine-tune mRNA regulation in early Xenopus development, and with Rkhd4, but not Rkhd1, will co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover.
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IF, E
圖像	Western blot analysis of RKHD3 in mouse skeletal muscle tissue lysate with RKHD3 antibody at 1 μg/mL. Immunofluorescence of RKHD3 in mouse skeletal muscle cells with RKHD3 antibody at 20 μg/mL.
說明書	Product Datasheet Protocol
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