品牌 |
Leading Biology | 貨號 |
APG03281G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality EMX1 antibody.
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分子量 |
28039 Da
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細胞定位 |
Antigen Cellular Localization:
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000269|PubMed:20887964}. Cytoplasm. Note=Might be shuttling between the nucleus and the cytoplasm
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宿主 |
Chicken
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種屬反應性 |
Human, Mouse, Rat
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靶點 |
EMX1; At least two isoforms of EMX1 are known to exist; this antibody will detect the longer isoform. EMX1 antibody is predicted to not cross-react with other EMX family members.
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亞型 |
IgY
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基因ID |
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UniProt ID |
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功能 |
Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system.
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總結(jié) |
EMX1 Antibody: EMX1 is a homeobox transcription factor involved in specifying cell fates in the developing central nervous system and it participates in the development of olfactory neurons. EMX1 is specifically expressed in the developing telencephalic cortex expression, where epxression is restricted to pyramidal neurons. EMX1 is a reliable marker of pyramidal neurons and pyramidal cell lineage. EMX1 has been shown to be one of the downstream target genes for Gli-Kruppel family member 3 (Gli3) transcription factor, which is a part of the Sonic hedgehog-Patched-Gli signaling pathway important in endocrine signaling.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, E
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圖像 |
Western blot analysis of EMX1 in rat liver tissue lysate with EMX1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide. |
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說明書 |
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數(shù)量 |
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