全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
AMM07749G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SEC62 antibody.
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分子量 |
45862 Da
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細胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein
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宿主 |
Rabbit
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種屬反應性 |
Human, Mouse, Rat
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靶點 |
SEC62; SEC62 antibody is predicted to not cross-react with other SEC proteins. Multiple isoforms of SEC62 are known to exist.
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亞型 |
IgG
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通用名 |
TLOC1
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基因ID |
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UniProt ID |
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功能 |
Required for preprotein translocation.
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總結(jié) |
SEC62 Antibody: SEC62 is an integral membrane protein located in the rough endoplasmic reticulum (ER) and is part of the SEC61-SEC62-SEC63 complex that is the central component of the protein translocation apparatus of the ER membrane. It is speculated that SEC61-SEC62-SEC63 may perform post-translational protein translocation into the ER and might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. Silencing of this gene with RNAi dramatically reduced the migration and invasive potential of numerous tumor cell lines, suggesting that it may be an attractive target for therapy of various tumors.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IHC-P, IF, E
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圖像 |
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說明書 |
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數(shù)量 |
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