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全部產(chǎn)品分類(lèi)
品牌 |
Leading Biology | 貨號(hào) |
APR17755G |
產(chǎn)品分類(lèi) |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Paralemmin3 antibody.
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分子量 |
71695 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Cell membrane; Lipid-anchor
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
PALM3; At least two isoforms of Paralemmin3 are known to exist; this antibody will only detect the longer isoform
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亞型 |
IgG
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基因ID |
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UniProt ID |
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功能 |
ATP-binding protein, which may act as a adapter in the Toll-like receptor (TLR) signaling.
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總結(jié) |
Paralemmin3 Antibody: Paralemmin3 is a recently identified protein that associates with the single immunoglobulin IL-1 receptor-related molecule (SIGIRR), a negative regulator of Toll-like receptor-interleukin 1 receptor signaling. Silencing of Paralemmin3 expression by RNAi inhibited the release of inflammatory cytokines in A549 cells after stimulation with lipopolysaccharide (LPS), suggesting Paralemmin3 may function as an adaptor in the LPS-TLR4 signaling pathway.
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形式 |
Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IF, ICC, E
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圖像 |
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說(shuō)明書(shū) |
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數(shù)量 |
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