品牌 |
Leading Biology | 貨號 |
APR10790G |
產品分類 |
Polyclonal Antibodies | 研究領域 |
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產品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ZIP13 antibody.
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分子量 |
39011 Da
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細胞定位 |
Antigen Cellular Localization:
Golgi apparatus membrane; Multi-pass membrane protein
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宿主 |
Rabbit
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種屬反應性 |
Human
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靶點 |
Slc39a13; At least two isoforms of ZIP13 are known to exist; this antibody will detect both isoforms. ZIP13 antibody is predicted to not cross-react with other ZIP family members.
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亞型 |
IgG
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通用名 |
ZIP13
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基因ID |
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UniProt ID |
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功能 |
Acts as a zinc-influx transporter.
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總結 |
ZIP13 Antibody: The zinc transporter ZIP13, also known as SLC39A13, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP13 is a multipass membrane protein that belongs to the ZIP transporter subfamily LIV-1. Mutations in ZIP13 have recently been shown to cause a spondylocheiro dysplastic form of Ehlers-Danlos syndrome (SCD-EDS), a generalized skeletal dysplasia involving mainly the spine with clinical abnormalities of the hands in addition to EDS-like features. Other experiments have shown that ZIP13 is required for proper connective tissue development and is involved in BMP/TGF- signaling pathways.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IHC-P, IF, E
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圖像 |
Western blot analysis of ZIP13 in K562 cell lysate with ZIP13 antibody at 1 μg/mL. Immunohistochemistry of ZIP13 in human spleen tissue with ZIP13 antibody at 2.5 μg/mL. Immunofluorescence of ZIP13 in human spleen tissue with ZIP13 antibody at 20 μg/mL. |
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說明書 |
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數(shù)量 |
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