品牌 |
Leading Biology | 貨號 |
APR10796G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ZIP7 antibody.
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分子量 |
50118 Da
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細胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane
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宿主 |
Rabbit
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種屬反應性 |
Human, Mouse, Rat
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靶點 |
SLC39A7;
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亞型 |
IgG
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通用名 |
HKE4, RING5
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基因ID |
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UniProt ID |
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功能 |
Zinc transporter, that transports Zn(2+) from the endoplasmic reticulum/Golgi apparatus to the cytosol. Transport is stimulated by growth factors, such as EGF, and Ca(2+), as well as by exogenous Zn(2+).
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總結 |
ZIP7 Antibody: The zinc transporter ZIP7, also known as SLC39A7, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP7 was initially identified while characterizing genes in the major histocompatibility complex on chromosome 17. ZIP7 mRNA is abundantly and widely expressed and the protein localizes to the Golgi apparatus. It functions to transport intracellular zinc from the Golgi apparatus to the cytoplasm of the cell. ZIP7 expression is expressed by zinc. ZIP7 has been suggested to act a hub for tyrosine kinase activation and may thus be a potential therapeutic target for diseases such as cancer where prevention of tyrosine kinase activation would be advantageous.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IHC-P, IF, E
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圖像 |
Western blot analysis of ZIP7 in mouse brain tissue lysate with ZIP7 antibody at 0.5 μg/mL. Immunohistochemistry of ZIP7 in human brain tissue with ZIP7 antibody at 2.5 μg/mL. Immunofluorescence of ZIP7 in human brain tissue with ZIP7 antibody at 20 μg/mL. |
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說明書 |
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數(shù)量 |
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