品牌 |
Leading Biology | 貨號 |
APR13568G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality STAU1 antibody.
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分子量 |
63182 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Rough endoplasmic reticulum Note=Localizes exclusively with the rough reticulum endoplasmic (RER)
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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靶點(diǎn) |
STAU1;
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亞型 |
IgG
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通用名 |
STAU
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基因ID |
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UniProt ID |
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功能 |
Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.
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總結(jié) |
STAU1 Antibody: STAU1 is a member of a family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human STAU1 also contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. STAU1 has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER. STAU1 is also known to interact with influenza ribonucleoproteins NS1, NP, and PA and is required for efficient viral replication.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IF, E
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圖像 |
Western blot analysis of STAU1 in rat brain tissue lysate with STAU1 antibody at (A) 1 and (B) 2 μg/mL. Immunohistochemistry of STAU1 in human brain tissue with STAU1 antibody at 10 μg/mL. Immunofluorescence of STAU1 in Human Brain cells with STAU1 antibody at 20 μg/mL. |
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說明書 |
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數(shù)量 |
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