品牌 |
Leading Biology | 貨號 |
AMM07815G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SIPA1L3 antibody.
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分子量 |
194610 Da
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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靶點 |
SIPA1L3;
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亞型 |
IgG
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通用名 |
KIAA0545, SPAL3
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基因ID |
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UniProt ID |
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總結(jié) |
SIPA1L3 Antibody: Signal-induced proliferation associated-like protein 2 (SIPA1L3) is a member of the SIPA1 family of RapGAPs. SIPA1L3 was cloned as a novel molecular component of tight junctions and adherens junctions, suggesting that may function to balance Rap1 by counteracting RapGEFs. Recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is possible that SIPA1L3 plays other roles development and cell proliferation.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IF, E
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圖像 |
Western blot analysis of SIPA1L3 in SK-N-SH lysate with SIPA1L3 antibody at 1 μg/mL. Immunohistochemistry of SIPA1L3 in human brain tissue with SIPA1L3 antibody at 5 μg/mL. Immunofluorescence of SIPA1L3 in Human Brain cells with SIPA1L3 antibody at 20 μg/mL. |
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說明書 |
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數(shù)量 |
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