Mimitin Antibody

APR08452G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR08452G		0.1 mg / ￥6950

大規(guī)格詢價(jià)

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訂購信息

安諾倫（北京）生物科技有限公司

Tel: 400-965-8633
Tel: 010-56256916
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Mimitin Antibody

品牌	Leading Biology	貨號(hào)	APR08452G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Mimitin antibody.
分子量	19856 Da
細(xì)胞定位	Antigen Cellular Localization: Mitochondrion.
宿主	Rabbit
種屬反應(yīng)性	Human
靶點(diǎn)	NDUFAF2;
亞型	IgG
通用名	NDUFA12L
基因ID	91942
UniProt ID	Q8N183
功能	Acts as a molecular chaperone for mitochondrial complex I assembly.
總結(jié)	Mimitin Antibody: Mimitin, a small mitochondrial protein, whose transcription is directly stimulated by c-Myc, is highly expressed in 80% of esophageal squamous cell carcinomas (ESCC). Suppression of Mimitin expression by RNA interference had no effect in cancerous cell lines such as human cervical carcinoma or hepatocarcinoma cell lines, but caused a decrease in cell proliferation in human glioblastoma, embryonic lung fibroblastic cells, and ESCC, suggesting Mimitin may play a special role in these types of cells. Mimitin expression is also regulated by MAPK kinases and IL-1, but not through the NF-κB-related pathway. It will interact with the microtubular protein MAP1S and can affect the activities of caspase-3 and -7 in cells stimulated to develop apoptosis. Other experiments suggest that Mimitin also acts as a molecular chaperone for the assembly of the mitochondrial complex I.
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IF, E
圖像	Western blot analysis of Mimitin in Raji cell lysate with Mimitin antibody at (A) 1 and (B) 2 μg/mL. Immunofluorescence of Mimitin in Raji cells with Mimitin antibody at 20 μg/mL.
說明書	Product Datasheet Protocol
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