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當(dāng)前位置：首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > TMEM16B Antibody

TMEM16B Antibody

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APR13754G 0.1 mg / ￥6950

TMEM16B Antibody

品牌

 Leading Biology

貨號(hào)

 APR13754G

產(chǎn)品分類

 Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TMEM16B antibody.

分子量
113969 Da

細(xì)胞定位
Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein

宿主
Rabbit

種屬反應(yīng)性
Human, Mouse, Rat

靶點(diǎn)
ANO2;

亞型
IgG

通用名
C12orf3, TMEM16B

基因ID

UniProt ID

功能
Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor-sensing receptors (OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process. May mediate light perception amplification in retina.

總結(jié)
TMEM16B Antibody: Calcium-activated chloride channels (CaCC) are present in many cell types and mediate physiological functions such as epithelial secretion, sensory signal transduction, and smooth muscle contraction. Subunits of these CaCC's include the transmembrane proteins TMEM16A and TMEM16B. TMEM16B is predicted to have eight transmembrane domains with both the amino and carboxy termini in the cytoplasm and is expressed in several tissues including olfactory sensory neurons as well as photoreceptors in mammalian retina. Like TMEM16A, TMEM16B is thought to form at least part of CaCC's but has different biophysical characteristics such as voltage dependence and unitary conductance.

形式
Liquid

儲(chǔ)存條件
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用
WB, IHC-P, IF, E

圖像

Western blot analysis of TMEM16B in rat brain tissue lysate with TMEM16B antibody at (A) 1 and (B) 2 μg/mL.

Immunohistochemistry of TMEM16B in human brain tissue with FRMPD4 antibody at 5 μg/mL.

Immunofluorescence of TMEM16B in Human Brain cells with TMEM16B antibody at 20 μg/mL.

說(shuō)明書(shū)

數(shù)量

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