品牌 |
Leading Biology | 貨號 |
APR12982G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Prosapip1 antibody.
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分子量 |
71791 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cytoplasm, cytoskeleton. Note=Detected at synapses, postsynaptic density, synaptic spines and dendrites
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse, Rat
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靶點(diǎn) |
ProSAPiP1;
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亞型 |
IgG
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通用名 |
KIAA0552, PROSAPIP1
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基因ID |
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UniProt ID |
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總結(jié) |
Prosapip1 Antibody: Prosapip1 is a binding partner of the postsynaptic density (PSD) protein ProSAP2/Shank3, a major scaffolding protein in excitatory brain synapses. Prosapip1 is thought to bind ProSAP2/Shank3 through ProSAP2/Shank3's PDZ domain and link it in turn to the Spine-associated Rap-Gap (SPAR). Prosapip1 shares significant homology with another PSD protein, PSD-Zip70, with both coding for a Fez1 domain that can be found in a total of four related protein, forming a novel family of scaffolding molecules termed ‘Fezzins'. Recent studies show that Prosapip1 can be found in endocrine cells in which it is localized primarily in the hormone-storing compartment of these cells, suggesting that Prosapip1 may have other functions in non-neuronal cells.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IF, E
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圖像 |
Western blot analysis of Prosapip1 in SK-N-SH cell lysate with Prosapip1 antibody at 1 μg/mL. Immunohistochemistry of Prosapip1 in rat brain tissue with Prosapip1 antibody at 2.5 μg/mL. Immunofluorescence of Prosapip 1 in rat brain tissue with Prosapip 1 antibody at 20 μg/mL. |
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說明書 |
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數(shù)量 |
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