全部產品分類
品牌 |
Leading Biology | 貨號 |
APR13797G |
產品分類 |
Polyclonal Antibodies | 研究領域 |
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產品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Transthyretin antibody.
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分子量 |
Predicted: 16 kDa Observed: 18 kDa
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細胞定位 |
Antigen Cellular Localization:
Secreted. Cytoplasm.
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宿主 |
Chicken
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種屬反應性 |
Human, Mouse, Rat
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靶點 |
TTR;
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亞型 |
IgY
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通用名 |
PALB
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基因ID |
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UniProt ID |
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功能 |
Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
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總結 |
Transthyretin Antibody: Transthyretin is a tetrameric carrier protein that transports thyroid hormones in the plasma and cerebrospinal fluid, and retinol (vitamin A) in the plasma. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart. The diseases caused by mutations include familial amyloidotic polyneuropathy, euthyroid hyperthyroxinemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, and carpal tunnel syndrome. It has also been suggested that Transthyretin plays an important role in the maintenance of normal cognitive processes during aging, neuropeptide processing and nerve regeneration. It has also been linked to several pathological conditions including Parkinson's disease, schizophrenia, and depression.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IHC-P, IF, E
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圖像 |
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說明書 |
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數(shù)量 |
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