全部產品分類
品牌 |
Leading Biology | 貨號 |
AMM07633G |
產品分類 |
Polyclonal Antibodies | 研究領域 |
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產品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Rkhd4 antibody.
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分子量 |
54173 Da
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細胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Cytoplasm, P-body. Note=Predominantly expressed in the cytoplasm and shuttles between the cytoplasm and the nucleus through the CRM1 export pathway
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宿主 |
Rabbit
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種屬反應性 |
Human, Mouse, Rat
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靶點 |
MEX3A;
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亞型 |
IgG
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通用名 |
RKHD4
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基因ID |
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UniProt ID |
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功能 |
RNA binding protein, may be involved in post- transcriptional regulatory mechanisms.
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總結 |
Rkhd4 Antibody: Rkhd4, also known as MEX3A is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module. MEX3 proteins, including Rkhd4, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway. These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms. While Rkhd2 has been suggested to be associated with susceptibility to essential hypertension type 8, the function of Rkhd4 remains unknown. Rkhd3 and Rkhd4, but not Rkhd2, co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IHC-P, IF, E
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圖像 |
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說明書 |
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數(shù)量 |
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