Aldh3A2 Antibody

APG01759G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APG01759G		0.1 mg / ￥6950

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安諾倫（北京）生物科技有限公司

Tel: 400-965-8633
Tel: 010-56256916
Inquiry@annoron.com

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Aldh3A2 Antibody

品牌	Leading Biology	貨號(hào)	APG01759G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Aldh3A2 antibody.
分子量	54848 Da
細(xì)胞定位	Antigen Cellular Localization: Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse
靶點(diǎn)	ALDH3A2; At least four isoforms of Aldh3A2 are known to exist. This antibody is predicted to have no cross-reactivity to Aldh3A1.
亞型	IgG
通用名	ALDH10, FALDH
基因ID	224
UniProt ID	P51648
功能	Catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid.
總結(jié)	Aldh3A2 Antibody: Aldh3A2 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh3A2 catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Mutations in the Aldh3A2 gene cause Sjogren-Larrson syndrome, an inherited neurocutaneous disorder. Patients with this disorder display ichthyosis, mental retardation and spastic diplegia. The pathogenesis of the cutaneous and neurological symptoms is thought to result from abnormal lipid accumulation in the membranes of skin and brain, the formation of aldehyde Schiff base adducts with amine-containing lipids or proteins, or defective eicosanoid metabolism.
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
圖像	Western blot analysis of Aldh3A2 in mouse liver lysate with Aldh3A2 antibody at (A) 1 and (B) 2 μg/mL.
說(shuō)明書	Product Datasheet Protocol
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